George Ford will return to the starting team for England with Eddie Jones expected to make four changes for this weekend's clash with Italy.
The Mail Online is reporting that Ford will reclaim the number 10 shirt with captain Owen Farrell reverting to inside-centre.
Fit-again Mako Vunipola and Kyle Sinckler is set to take over from Ellis Genge and Will Stuart in the England team to play Italy with Courtney Lawes 50/50 to replace Jonny Hill in the second-row.
England team to play Italy (Possible)
Anthony Watson, Elliot Daly, Henry Slade, Owen Farrell, Jonny May, George Ford, Ben Youngs; Mako Vunipola, Jamie George, Kyle Sinckler, Maro Itoje, Courtney Lawes, Mark Wilson, Tom Curry, Billy Vunipola
When is England v Italy?
Saturday, February 13.
What time is kick-off?
The match will start at 2.15pm GMT.
What TV channel is it on?
ITV will broadcast this fixture, as they have the rights to all of England's home matches.
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Five stars pushing for spot in Warren Gatland’s Lions squad
Here, we look at five players who significantly boosted their chances during the opening weekend of the 2021 Guinness Six Nations.
Hamish Watson
A stalwart of the Scotland back-row, Watson has popped back on the radar through a stunning return to form for Scotland. The flanker was a major force in this historic win against England at Twickenham, making telling contributions in both attack and defence. A class act.
Robbie Henshaw
Ireland's best player in Cardiff. Key to the away sides try at the end of the first half, the powerhouse carried 18 times for 116m and made six tackles - despite missing 10 minutes of the game for a Head Injury Assessment. Probably the most in form centre around at the moment.
Louis Rees-Zammit
Wales again struggled to get the ball to the Gloucester winger, who has only seen the ball a handful of times in his fledgling Test career to date. However, when he did get it, he moved like lightening and finished in the corner in remarkable fashion. Gatland will like what he's seen of the youngster so far.
Jonny Gray
The Exeter Chiefs man produced a towering performance for his country and forced the likes of Maro Itoje into rare mistakes. A statement showing from a Lions candidate.
Wyn Jones
With England's Mako Vunipola out injured, Jones proved himself to be the most dynamic loosehead from across the home nations. He carried really well, making an impressive 44m from 10 carries with ball in hand and held his own against Andrew Porter. Deserved his Man Of The Match award, and definitely enters the race for a place on the Lions tour.
Because Jonny Gray habitually makes 20+ carries and 20+ tackles a game, it's easy to forget how bloody good he is. His standards are set so high that folk take them for granted. Absolutely colossal today. Adding more gears and snarl to his game at Exeter.